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Nitric oxide dilates blood vessels facilitating blood delivery to the muscles (and organs in general). This way the nutrient delivery is optimized when most needed. In turn, this stimulates muscle growth, strength and endurance. HSNstore supplies nitric oxide stimulators as a single supplement, or combined with creatine and stimulants.

Generally, the majority of athletes whether professional or amateur, aim to gain greater muscle efficiency and increase the blood supply for the purposes of: 1. Increasing the dose of nutrients and oxygen to the muscles, and 2. Promoting the elimination of lactic acid (one of the main causes of muscle fatigue).

These two objectives are very important both for athletes seeking greater muscle development, and for those whose focus is more on bettering their personal records by improving their speed or strength.

For this reason there are currently many athletes that choose to buy nitric oxide stimulators.

Nitric oxide, also called nitrogen monoxide (NO), is a gas that is generated in very small doses endogenously in our bodies by the amino acid L-arginine. One of the most outstanding functions of NO is its ability to promote the dilation or widening of the blood vessels.

This widening causes a higher volume of blood to reach the muscle cells.

This means that the muscles will receive more oxygen and nutrients and will additionally speed up the removal of waste substances.

All this translates into an improved performance, increased strength, improved recovery, as well as further development of muscle mass.

What are nitric oxide stimulators or vasodilator supplement products?

They are types of supplements which include ingredients capable of activating mechanisms that promote NO stimulation and that therefore increase vascularisation.

The two ingredients used to promote vasodilation are l-arginine and l-citrulline.

L-arginine is considered a non-essential amino acid (our bodies can synthesise it) and is part of many proteins that are in our daily diet. Once the digestive tract absorbs it, arginine travels through the blood to the tissues or organs that require it at that moment.

Once internalised within the cell through the ecytoplasmic enzyme nitric oxide synthase effect (NO synthase), L-arginine promotes the synthesis of nitric oxide.

L-arginine and L-Citrulline will be exchanged for a larger quantity of nitric oxide.

New pre-workout products containing l-arginine are beginning to add additional citrulline malate, as this ingredient has the ability to increase arginine levels in blood plasma endogenously.

In fact, some studies show that taking l-citrulline increases arginine levels without directly taking arginine itself.

Other properties/benefits of nitric oxide

Raises NO levels within the body in addition to other beneficial properties:

  • It helps to fight against infectious organisms, especially bacteria.
  • It has an anti-inflammatory effect.
  • It promotes vasodilation of the circulatory system. This property can be of particular interest for people suffering from hypertension or heart problems.
  • NO also has blood thinning effects, helping to prevent the formation of clots that cause heart attacks.
  • What makes this substance a great benefit for memory and cognitive functions over the long term, is that it increases cerebral irrigation and acts as a neurotransmitter.
  • It promotes angiogenesis, which is the creation of new blood vessels that will provide a higher percentage of nutrients and oxygen to the muscles, which in turn will accelerate the removal of lactate, thereby improving performance.
  • It causes an increase in the number of mitochondria (mitochondrial biogenesis) helping to improve the use of fatty acids by skeletal muscle. Its increase also generates a greater quantity of mitochondrial enzymes, vital for increased production of ATP.
  • It promotes the regeneration of muscles by accelerating recovery processes after physical activity, thanks to its ability to encourage cell division.
  • It also promotes muscle hypertrophy.
  • It helps to protect the integrity of muscle fibres during exercise.
  • We also mustn't forget its benefits in improving sexual intercourse, because it impinges on the same metabolic pathway that the well-known drug viagra does, causing a similar effect, although to a lesser extent. It is very beneficial for people that suffer from erectile dysfunction.

How to take nitric oxide stimulator supplements

Supplementation with L-arginine and L-citrulline promotes a greater production of nitric oxide. However, nitric oxide cannot be stored in the body, which means that these amino acids should be taken daily immediately before exercise.

We should take note that as this is a molecule that is synthesised in the body, we should encourage it to additionally generate its own nitrous oxide. Otherwise the production of nitrous oxide that occurs endogenously may be reduced.

Our body is a machine that generates only what it needs. Therefore, whenever there is a continuous and sufficient supply of NO, there wouldn't be any necessity to synthesise it.

Taking turns with different supplements is therefore recommended. For example, taking nitric oxide stimulators for two or three months, then taking a break for two or three months, before taking a different supplement. Nitric oxide enhancers are products that should be taken with caution and awareness of their effects.

Side effects of NO stimulators

People who have hypotension (low blood pressure) should avoid consumption of these products, since the vasodilation that they bring about causes a lowering of blood pressure. Taking nitric oxide stimulators accelerates ageing, since they are substances which release large amounts of free radicals.

Accompanying these products with antioxidants is avisable, since it will mitigate the effects of free radicals.

Using these supplements can cause problems with digestion. When eating the blood flow is focused on the stomach, which is vital for the assimilation of nutrients.

However, if we take nitric oxide stimulator products, the blood can be concentrated in the muscle tissues, which is the reason for the possible digestion problems.

To avoid this issue we shouldn't eat food two hours before taking nitric oxide and training.